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International Journal of Neurology Sciences

Vol. 5, Issue 1, Part A (2023)

The role of remote ischemic preconditioning of the brain in the treatment of patients with mild Alzheimer disease

Author(s):

Fani Tsolaki

Abstract:

Background: In the current paper we are presenting the results of a crossover study aiming at investigating the role of ischemic remote preconditioning in the cognitive status of patients with Alzheimer’s disease and concurrent peripheral arteriopathy. 
Methods: We recruited 10 patients with mild Alzheimer’s disease and Rutherford stage 3 peripheral arteriopathy. After a thorough initial control, the patients were instructed and entered a standardized walking Programme for 2 months, followed by a Mini-Mental State Examination (MMSE) test. This was followed by a period of cessation of exercise also followed by a MMSE test. 
Results/Conclusion: Remote ischemic postconditioning resulting after daily claudication appearance through two months structured exercise led to a very significant improvement in MMSE. Amelioration was not preserved when remote postconditioning was discontinued.
 

Pages: 29-30  |  495 Views  194 Downloads


International Journal of Neurology Sciences
How to cite this article:
Fani Tsolaki. The role of remote ischemic preconditioning of the brain in the treatment of patients with mild Alzheimer disease. Int. J. Neurol. Sci. 2023;5(1):29-30. DOI: 10.33545/26646161.2023.v5.i1a.12